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Screening & Early Detection

Detecting lung cancer early, when it is easiest to treat, can save lives.

Currently, only 16% of lung cancers are diagnosed while the tumor is still localized – that is, in its earliest stages of growth. A major challenge is that most people with lung cancer only have symptoms when they are in later stages of disease. In fact, it does happen sometimes among those who are diagnosed early that their lung cancer was discovered during treatment for an unrelated medical issue.

Screening for cancer means checking for cancer before there are any symptoms. Examples of commonly used screening tests for cancer are mammograms for breast cancer, colonoscopies for colon cancer, and the Pap test and HPV tests for cervical cancer. There is not yet a comparable reliable and broadly available screening test for lung cancer that can catch the disease early. Chest X-rays are not recommended for screening because they often miss early-stage lung cancers and have not resulted in decreased mortality. Likewise for sputum cytology, a test that checks for abnormal cells in sputum. There is ongoing research toward developing such a reliable and broadly available lung cancer screening test that can be used for all.

Low-dose CT scan (LDCT)

What is available now, and has proven to be effective for lung cancer screening among high-risk individuals, is a low-dose CT scan (LDCT), which is much more sensitive than chest X-rays. LDCT is recommended for early-detection screening, but only in these high-risk individuals. The benefits of LDCT for high-risk individuals were confirmed by the National Lung Screen Trial (NLST). It is therefore recommended as a yearly screening procedure.

Techniques in low-dose CT scans reduce radiation risk, decreasing the amount of radiation up to 10 times, compared to standard chest CT scans. By now, annual screening with LDCT is recommended in the U.S. and in some European countries for high-risk patients, i.e. patients who meet the following criteria:

  • aged 50-80 years
  • have a 20 pack-year smoking history (1 pack per day for 20 years or 2 packs for 10 years)
  • currently smoke or have quit smoking within the past 15 years

 

Any information provided on diseases is intended for the purpose of providing general information to the public and under no circumstances can it substitute the advice of a doctor or other competent health professional.