Panos Z. Anastasiadis, PhD, is professor of cancer biology at the Mayo Clinic College of Medicine, and consultant at the Mayo Clinic Cancer Center. Dr. Anastasiadis has served as director of the Mayo Clinic Graduate School in Florida, and as chair of Mayo Clinic’s enterprise-wide Department of Cancer Biology. He is the co-director of the Cancer Cell Biology program of the Mayo Clinic Cancer Center, member of the executive committee for the Mayo Clinic Center for Biomedical Discovery, and member of the executive committee for precision cancer therapeutics at the Mayo Clinic Center for Individualized Medicine.

His research interests are focused on signaling events that regulate cell-cell adhesion or cell migration/invasion and transformed cell growth. His expertise includes cell-cell adhesion signaling, regulation of Rho GTPases during cell adhesion and/or migration, as well as the establishment of cell polarity in both adherent and migrating cells. Additionally, his lab uses organotypic 3D cultures, genomics, proteomics and antibody-based methodologies as a means of identifying oncogenic pathways that are activated in individual patient’s tumors and can be targeted for therapy on an individualized basis with available therapeutics. In collaboration with the Center for Individualized Medicine and the biomarker discovery lab, he has launched the Ex Vivo clinical project in multiple cancer types, and across Mayo Clinic sites. He has served as a standing member of the Tumor Progression and Metastasis study section at the National Institutes of Health (NIH), as Chair of the Neural Regulation of Cancer NIH study section, and currently as member of the R35 Maximizing Investigators Research Awards (MIRA) study section at the National Institute of General Medical Sciences (NIGMS).